{"entity":{"id":"nct07700160","kind":"trial","name":"First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of VBC108 in advanced solid tumours, run by VelaVigo Bio Inc, now recruiting.","summary":"First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors is a phase 1/2 interventional study registered as NCT07700160 by VelaVigo Bio Inc, with 230 participants planned, started 2026-07-30 and due to reach its primary completion in 2029-07-07. Interventions recorded: VBC108.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07700160","url":"https://clinicaltrials.gov/study/NCT07700160"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["velavigo"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07700160","phase":"1/2","setting":"Phase 1/2a Open-label Clinical Trial Evaluating VBC108, a CLDN18.2 and CDH17-directed Bi-specific Antibody Drug Conjugate, in Participants With Advanced Malignant Solid Tumors","sponsor":"VelaVigo Bio Inc","participation":[{"nct":"NCT07700160","source":"https://clinicaltrials.gov/study/NCT07700160","fetchedAt":"2026-10-07T16:55:59.097Z","studySha256":"48b81b4e17fb632310636da2e3aa8f0ff6389dcc7a62a7ea70ed12738ebd0824","overallStatus":"RECRUITING","lastUpdatePosted":"2026-09-01","leadSponsor":"VelaVigo Bio Inc","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":230,"enrolmentType":"ESTIMATED","siteCount":12,"recruitingSiteCount":5,"countries":["Australia","China","United States"]}],"started":"2026-07-30","startedType":"actual","enrolled":230,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07700160/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"company":[{"id":"velavigo","kind":"company","name":"VelaVigo","route":"/companies/velavigo/"}]}}