{"entity":{"id":"nct07636785","kind":"trial","name":"A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors","aka":["SPKTAHC"],"tldr":"A phase 1/2 trial of VMD-102 in hepatocellular carcinoma, uveal melanoma, renal cell carcinoma, non-small-cell lung cancer and colorectal cancer, run by VM Discovery, Inc., now recruiting.","summary":"A Phase 1 and 2 Study of VMD-102 in Hepatocellular Carcinoma and Other Solid Tumors is a phase 1/2 interventional study registered as NCT07636785 by VM Discovery, Inc., with 111 participants planned, started 2026-07-16 and due to reach its primary completion in 2031-05. Interventions recorded: VMD-102.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07636785","url":"https://clinicaltrials.gov/study/NCT07636785"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["hcc","uveal-melanoma","rcc","nsclc","colorectal","hcc-advanced"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07636785","phase":"1/2","setting":"A Phase 1 and 2 First-in-human, Open-label, Multicenter Study to Assess the Safety, Tolerability and Preliminary Efficacy of VMD-102 in Participants With Hepatocellular Carcinoma and Other Advanced Solid Tumors","sponsor":"VM Discovery, Inc.","participation":[{"nct":"NCT07636785","source":"https://clinicaltrials.gov/study/NCT07636785","fetchedAt":"2026-10-07T16:55:52.872Z","studySha256":"19506be7ae2d67bb210e2173953f9d9c7e007548395b9e0d2e291b285d08a49c","overallStatus":"RECRUITING","lastUpdatePosted":"2026-08-19","leadSponsor":"VM Discovery, Inc.","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":111,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["United States"]}],"started":"2026-07-16","startedType":"actual","enrolled":111,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07636785/","neighbours":{"cancer":[{"id":"hcc-advanced","kind":"cancer","name":"Advanced hepatocellular carcinoma (BCLC C)","route":"/cancers/hcc-advanced/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"rcc","kind":"cancer","name":"Renal cell carcinoma","route":"/cancers/rcc/"},{"id":"uveal-melanoma","kind":"cancer","name":"Uveal melanoma","route":"/cancers/uveal-melanoma/"}]}}