{"entity":{"id":"nct07586813","kind":"trial","name":"Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gastrointestinal Solid Tumors","aka":["N01-A-PICIT-GI"],"tldr":"A phase 2 trial of tretinoin (all-trans retinoic acid, ATRA) in pancreatic cancer, run by Peking University People's Hospital, now recruiting.","summary":"Romiplostim N01 Plus ATRA for Persistent Isolated Chemotherapy-Induced Thrombocytopenia After Complete Remission of Gastrointestinal Solid Tumors is a phase 2, randomised interventional study registered as NCT07586813 by Peking University People's Hospital, with a registry enrolment figure of 220 participants, started 2025-12-22 and due to reach its primary completion in 2027-10-31. Interventions recorded: Romiplostim N01; All-trans retinoic acid. Conditions listed: Persistent Isolated Chemotherapy-Induced Thrombocytopenia; Chemotherapy-Induced Thrombocytopenia; Gastrointestinal Neoplasms; Pancreatic Cancer; Colorectal Cancer. Primary outcome: Overall Platelet Response Rate at Week 12. Pancreatic eligibility wording from the registry: \"Prior diagnosis of a gastrointestinal/digestive system solid tumor, including but not limited to gastrointestinal tract, pancreatic, or colorectal cancer\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07586813","url":"https://clinicaltrials.gov/study/NCT07586813"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":["tretinoin-atra"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07586813","phase":"2","setting":"A Prospective, Randomized, Open-Label, Controlled Study of Romiplostim N01 Combined With All-Trans Retinoic Acid Versus Romiplostim N01 Alone for Persistent Isolated Chemotherapy-Induced Thrombocytopenia in Patients With Complete Remission of Gastrointestinal Solid Tumors","sponsor":"Peking University People's Hospital","participation":[{"nct":"NCT07586813","source":"https://clinicaltrials.gov/study/NCT07586813","fetchedAt":"2026-10-07T16:55:50.238Z","studySha256":"737f9c3c27c0e9d149845cb6a3c6daffa0a6a82e45a9339cc3885b5921e68870","overallStatus":"RECRUITING","lastUpdatePosted":"2026-05-14","leadSponsor":"Peking University People's Hospital","collaboratorCount":8,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":220,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2025-12-22","startedType":"actual","enrolled":220,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07586813/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"drug":[{"id":"tretinoin-atra","kind":"drug","name":"Tretinoin (all-trans retinoic acid, ATRA)","route":"/drugs/tretinoin-atra/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}