{"entity":{"id":"nct07429266","kind":"trial","name":"INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV)","aka":["INTREPID"],"tldr":"A phase 3 trial of Sapablursen in myeloproliferative neoplasms, run by Ono Pharmaceutical Co., Ltd., now recruiting.","summary":"INTREPID: A Study of Sapablursen Evaluating the Safety and Efficacy in Participants With Polycythemia Vera (PV) is a phase 3 interventional study registered as NCT07429266 by Ono Pharmaceutical Co., Ltd., with 250 participants planned, started 2026-05-25 and due to reach its primary completion in 2028-09. Interventions recorded: Sapablursen and Placebo.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07429266","url":"https://clinicaltrials.gov/study/NCT07429266"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["myeloproliferative-neoplasms","polycythaemia-vera"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["deciphera"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07429266","phase":"3","setting":"A Phase 3 Randomized, Double-blind, Placebo-controlled Global Study of Sapablursen in Polycythemia Vera","sponsor":"Ono Pharmaceutical Co., Ltd.","participation":[{"nct":"NCT07429266","source":"https://clinicaltrials.gov/study/NCT07429266","fetchedAt":"2026-10-07T16:55:44.977Z","studySha256":"e80c3ed8ddc94e1e8299b4b03603d4d188ae7527e5c327a01152a9cc530c3d43","overallStatus":"RECRUITING","lastUpdatePosted":"2026-10-05","leadSponsor":"Ono Pharmaceutical Co., Ltd.","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":250,"enrolmentType":"ESTIMATED","siteCount":17,"recruitingSiteCount":17,"countries":["Australia","Japan","Poland","United Kingdom","United States"]}],"started":"2026-05-25","startedType":"actual","enrolled":250,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07429266/","neighbours":{"cancer":[{"id":"myeloproliferative-neoplasms","kind":"cancer","name":"Myeloproliferative neoplasms (PV, ET, myelofibrosis)","route":"/cancers/myeloproliferative-neoplasms/"},{"id":"polycythaemia-vera","kind":"cancer","name":"Polycythaemia vera (PV)","route":"/cancers/polycythaemia-vera/"}],"company":[{"id":"deciphera","kind":"company","name":"Deciphera Pharmaceuticals (Ono)","route":"/companies/deciphera/"}]}}