{"entity":{"id":"nct07372300","kind":"trial","name":"Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer","aka":["mEHT"],"tldr":"A phase 3 trial in colorectal cancer, run by Shih-Kai Hung, now recruiting.","summary":"Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer is a phase 3, randomised interventional study registered as NCT07372300 by Shih-Kai Hung, with a registry enrolment figure of 126 participants, started 2025-09-23 and due to reach its primary completion in 2027-12-31. Interventions recorded: Hyperthermia. Conditions listed: Locally Advanced Rectal Carcinoma. Primary outcome: Down-staging Rate. Colorectal eligibility wording from the registry: \"Initial pathological diagnosis of adenocarcinoma of the rectum\". Sites: Taiwan. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07372300","url":"https://clinicaltrials.gov/study/NCT07372300"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07372300","phase":"3","setting":"The Efficacy of Combination of Modulated Electro-Hyperthermia(mEHT) in The Multimodality Management in Locally Advanced Rectal Cancer: A Multicenter Phase 3 Randomized Control Trial.","sponsor":"Shih-Kai Hung","participation":[{"nct":"NCT07372300","source":"https://clinicaltrials.gov/study/NCT07372300","fetchedAt":"2026-10-07T16:55:42.201Z","studySha256":"0d443a24af4f1b8829cf3e22d2ea7e2de79b5070bb70fe3beb34fd81ff6f8809","overallStatus":"RECRUITING","lastUpdatePosted":"2026-01-28","leadSponsor":"Shih-Kai Hung","collaboratorCount":1,"minimumAge":"20 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":126,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["Taiwan"]}],"started":"2025-09-23","startedType":"actual","enrolled":126,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07372300/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}