{"entity":{"id":"nct07359066","kind":"trial","name":"An Open-label, First-in-Human, Dose-Escalation and Dose-Expansion Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPR1020 in Patients With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of SRP1020 in advanced solid tumours, run by Shanghai SciBrunch Therapeutics Co., Ltd., now recruiting.","summary":"An Open-label, First-in-Human, Dose-Escalation and Dose-Expansion Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPR1020 in Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT07359066 by Shanghai SciBrunch Therapeutics Co., Ltd., with 210 participants planned, started 2026-01-08 and due to reach its primary completion in 2028-02. Interventions recorded: SRP1020.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07359066","url":"https://clinicaltrials.gov/study/NCT07359066"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07359066","phase":"1/2","setting":"An Open-label, First-in-Human, Dose-Escalation and Dose-Expansion Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPR1020 in Patients With Advanced Solid Tumors","sponsor":"Shanghai SciBrunch Therapeutics Co., Ltd.","participation":[{"nct":"NCT07359066","source":"https://clinicaltrials.gov/study/NCT07359066","fetchedAt":"2026-10-07T16:55:42.201Z","studySha256":"0dacda91ad72c3c9f79158f80673fbc56a7aed8f3855f2fa8ce9c5f5b3aa88d4","overallStatus":"RECRUITING","lastUpdatePosted":"2026-02-05","leadSponsor":"Shanghai SciBrunch Therapeutics Co., Ltd.","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":210,"enrolmentType":"ESTIMATED","siteCount":2,"recruitingSiteCount":1,"countries":["China"]}],"started":"2026-01-08","startedType":"actual","enrolled":210,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07359066/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}]}}