{"entity":{"id":"nct07336446","kind":"trial","name":"A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs","aka":["ANDROMEDA"],"tldr":"This study tests a PARP inhibitor; the registry reports that it is active not recruiting.","summary":"The registry lists NCT07336446 as active not recruiting, last updated 2026-10-02. Enrolment is 6 actual participants. Interventions: AZD9750, AZD5305. Primary measures include Number of participants with dose-limiting toxicity (DLT), as defined in the protocol (Part A only); Number of participants with Adverse Events and Serious Adverse Events. No results are posted in the registry; this does not exclude separate publications.","status":"active","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT07336446","url":"https://clinicaltrials.gov/study/NCT07336446"}],"tags":["ctgov-ingest"],"related":[],"cancers":["prostate"],"sections":[],"technologies":[],"targets":["parp"],"drugs":["azd9750","saruparib"],"companies":["astrazeneca"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07336446","phase":"1/2","setting":"A Phase I/II, Modular, Open-Label, Multi-Centre Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of AZD9750 as Monotherapy and in Combination With Other Anticancer Agents in Participants With Metastatic Prostate Cancer (ANDROMEDA)","sponsor":"AstraZeneca","participation":[{"nct":"NCT07336446","source":"https://clinicaltrials.gov/study/NCT07336446","fetchedAt":"2026-10-07T16:55:41.039Z","studySha256":"ae01ed10972ae79cf78ca714e1a43e1f5312f7b6538fa346968a7e97bd99b7cf","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-10-02","leadSponsor":"AstraZeneca","collaboratorCount":0,"minimumAge":"18 Years","sex":"MALE","healthyVolunteers":false,"hasEligibility":true,"enrolment":6,"enrolmentType":"ACTUAL","siteCount":5,"recruitingSiteCount":0,"countries":["Australia","Japan","United Kingdom","United States"]}],"started":"2026-01-27","startedType":"actual","enrolled":6,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07336446/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"target":[{"id":"parp","kind":"target","name":"PARP","route":"/targets/parp/"}],"drug":[{"id":"azd9750","kind":"drug","name":"AZD9750","route":"/drugs/azd9750/"},{"id":"saruparib","kind":"drug","name":"Saruparib","route":"/drugs/saruparib/"}],"company":[{"id":"astrazeneca","kind":"company","name":"AstraZeneca","route":"/companies/astrazeneca/"}]}}