{"entity":{"id":"nct07333651","kind":"trial","name":"125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Li Min, not yet recruiting.","summary":"125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07333651 by Li Min, with a registry enrolment figure of 90 participants, started 2026-01 and due to reach its primary completion in 2027-01-01. Interventions recorded: Standard-of-Care Systemic Therapy; 125I Seed Implantation. Conditions listed: Oligometastatic Disease. Primary outcome: Progression-Free Survival (PFS). Colorectal eligibility wording from the registry: \"* Histologically or cytologically confirmed metastatic non-small cell lung cancer (NSCLC) or colorectal cancer (CRC)\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07333651","url":"https://clinicaltrials.gov/study/NCT07333651"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07333651","phase":"2","setting":"Standard-of-Care Systemic Therapy With or Without Image-Guided 125I Seed Implantation in Patients With Oligoprogressive Metastatic Non-Small Cell Lung Cancer or Colorectal Cancer: An Open-Label, Randomized, Controlled Phase 2 Study","sponsor":"Li Min","participation":[{"nct":"NCT07333651","source":"https://clinicaltrials.gov/study/NCT07333651","fetchedAt":"2026-10-07T16:55:41.039Z","studySha256":"8ec5abad1f49bf21daef9be8c68cec37acc5b5a0a1a1355795d56f32dfa2693a","overallStatus":"NOT_YET_RECRUITING","lastUpdatePosted":"2026-01-12","leadSponsor":"Li Min","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":90,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":0,"countries":["China"]}],"started":"2026-01","startedType":"estimated","enrolled":90,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07333651/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}