{"entity":{"id":"nct07284394","kind":"trial","name":"Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk of Recurrence of Their Disease","aka":["PACHA-02"],"tldr":"A phase 3 trial in colorectal cancer, run by UNICANCER, not yet recruiting.","summary":"Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk of Recurrence of Their Disease is a phase 3, randomised interventional study registered as NCT07284394 by UNICANCER, with a registry enrolment figure of 272 participants, started 2026-07 and due to reach its primary completion in 2031-01. Interventions recorded: Arterial catheter infusion chemotherapy; IV Chemotherapy (Regimen 1). Conditions listed: Colorectal Adenocarcinoma Metastatic in the Liver; Colorectal Cancer. Primary outcome: Recurrence-free survival (RFS). No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07284394","url":"https://clinicaltrials.gov/study/NCT07284394"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["unicancer"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07284394","phase":"3","setting":"Postoperative Hepatic Arterial Chemotherapy After Resection of Colorectal Liver Metastases in Patients at High Risk of Recurrence","sponsor":"UNICANCER","participation":[{"nct":"NCT07284394","source":"https://clinicaltrials.gov/study/NCT07284394","fetchedAt":"2026-10-07T16:55:38.126Z","studySha256":"40f3ceade8b652bb33d5efbbf7a9bbac9147b834dc6021ffe876b08ce117b964","overallStatus":"NOT_YET_RECRUITING","lastUpdatePosted":"2026-05-26","leadSponsor":"UNICANCER","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":272,"enrolmentType":"ESTIMATED","siteCount":0,"recruitingSiteCount":0}],"started":"2026-07","startedType":"estimated","enrolled":272,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07284394/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"company":[{"id":"unicancer","kind":"company","name":"UNICANCER","route":"/companies/unicancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}