{"entity":{"id":"nct07242274","kind":"trial","name":"Phase 3 Trial of JMKX001899 Versus Docetaxel in Previously Treated Advanced or Metastatic KRAS G12C-Mutant NSCLC","aka":[],"tldr":"A phase 3 trial of docetaxel in lung cancer, run by Jemincare, not yet recruiting.","summary":"Phase 3 Trial of JMKX001899 Versus Docetaxel in Previously Treated Advanced or Metastatic KRAS G12C-Mutant NSCLC is a phase 3, randomised interventional study registered as NCT07242274 by Jemincare, with a registry enrolment figure of 472 participants, started 2025-12-31 and due to reach its primary completion in 2027-12-31. Interventions recorded: JMKX001899; Docetaxel. Conditions listed: NSCLC (Non-small Cell Lung Cancer). Primary outcome: PFS. Lung eligibility wording from the registry: \"Histologically or cytologically confirmed NSCLC\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07242274","url":"https://clinicaltrials.gov/study/NCT07242274"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["kras-g12c-nsclc"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["docetaxel"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07242274","phase":"3","setting":"A Multicenter, Randomized, Open-Label, Phase 3 Study Evaluating the Efficacy and Safety of JMKX001899 Versus Docetaxel in Previously Treated Patients With KRAS G12C-Mutant Advanced or Metastatic Non-Small Cell Lung Cancer","sponsor":"Jemincare","participation":[{"nct":"NCT07242274","source":"https://clinicaltrials.gov/study/NCT07242274","fetchedAt":"2026-10-07T16:55:34.394Z","studySha256":"098b5e658de61ba72d62cd6c8ecebb869bec52410ee527c35f085e597532277d","overallStatus":"NOT_YET_RECRUITING","lastUpdatePosted":"2025-11-21","leadSponsor":"Jemincare","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":472,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":0,"countries":["China"]}],"started":"2025-12-31","startedType":"estimated","enrolled":472,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07242274/","neighbours":{"cancer":[{"id":"kras-g12c-nsclc","kind":"cancer","name":"KRAS G12C-mutant non-small-cell lung cancer","route":"/cancers/kras-g12c-nsclc/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"docetaxel","kind":"drug","name":"Docetaxel","route":"/drugs/docetaxel/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}