{"entity":{"id":"nct07217301","kind":"trial","name":"A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer","aka":["MarsLight-11"],"tldr":"A phase 3 trial testing TAK-928 in non-small-cell lung cancer, now recruiting.","summary":"A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer is a phase 3 interventional study registered as NCT07217301, led by Takeda with Innovent Biologics (Suzhou), and recruiting on the registry. Official title: A Randomised, Open Label, Multicenter, Phase 3 Trial Evaluating the Efficacy and Safety of TAK-928 Versus Docetaxel in Participants With Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Disease Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy. Planned enrolment is 600 participants (estimated). The study started in 2025-11-26 and primary completion is expected in 2028-11-01. No results have been posted on ClinicalTrials.gov.","status":"recruiting","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT07217301","url":"https://clinicaltrials.gov/study/NCT07217301"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["tak-928"],"companies":["takeda"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07217301","phase":"3","setting":"A Randomized, Open Label, Multicenter, Phase 3 Trial Evaluating the Efficacy and Safety of TAK-928 Versus Docetaxel in Participants With Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Disease Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy","sponsor":"Takeda","participation":[{"nct":"NCT07217301","source":"https://clinicaltrials.gov/study/NCT07217301","fetchedAt":"2026-10-07T16:55:33.599Z","studySha256":"5417ed5382cd4bc55fad56f237f3c3632567af1a34dd07fe324b6f96fb305259","overallStatus":"RECRUITING","lastUpdatePosted":"2026-08-04","leadSponsor":"Takeda","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":600,"enrolmentType":"ESTIMATED","siteCount":46,"recruitingSiteCount":33,"countries":["China","Japan","United States"]}],"started":"2025-11-26","startedType":"actual","enrolled":600,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07217301/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"tak-928","kind":"drug","name":"TAK-928","route":"/drugs/tak-928/"}],"company":[{"id":"takeda","kind":"company","name":"Takeda","route":"/companies/takeda/"}]}}