{"entity":{"id":"nct07213830","kind":"trial","name":"A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies","aka":[],"tldr":"A phase 1/2 trial of IPN01203 in advanced solid tumours, run by Ipsen, now recruiting.","summary":"A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies is a phase 1/2 interventional study registered as NCT07213830 by Ipsen, with 102 participants planned, started 2026-02-06 and due to reach its primary completion in 2032-07-14. Interventions recorded: IPN01203.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07213830","url":"https://clinicaltrials.gov/study/NCT07213830"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["ipsen"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07213830","phase":"1/2","setting":"An Open-label, Phase I/II First in Human, Dose Escalation, Optimisation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Participants With Locally Advanced or Metastatic Solid Tumours Who Have Progressed on or After Immune Checkpoint Inhibitor Therapies","sponsor":"Ipsen","participation":[{"nct":"NCT07213830","source":"https://clinicaltrials.gov/study/NCT07213830","fetchedAt":"2026-10-07T16:55:33.599Z","studySha256":"76e70b2bc20e0dff0a54443074cf17652d2633d299fe25b79351a523f680906c","overallStatus":"RECRUITING","lastUpdatePosted":"2026-09-03","leadSponsor":"Ipsen","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":102,"enrolmentType":"ESTIMATED","siteCount":10,"recruitingSiteCount":10,"countries":["Canada","France","Spain","United States"]}],"started":"2026-02-06","startedType":"actual","enrolled":102,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07213830/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"company":[{"id":"ipsen","kind":"company","name":"Ipsen","route":"/companies/ipsen/"}]}}