{"entity":{"id":"nct07198165","kind":"trial","name":"SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Ruijin Hospital, now recruiting.","summary":"SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARC is a phase 2, randomised interventional study registered as NCT07198165 by Ruijin Hospital, with a registry enrolment figure of 104 participants, started 2025-09-05 and due to reach its primary completion in 2030-12-31. Interventions recorded: PD-1 inhibitor based immunotherapy. Conditions listed: Rectal Cancer; Rectal Adenocarcinoma; Rectal Cancer, Radiotherapy; Rectal Cancer Patients; Immunotherapy; Total Neoadjuvant Therapy; Total Neoadjuvant Treatment; Targeted Therapy; Chemoradiotherapy. Primary outcome: Complete Response rate. Colorectal eligibility wording from the registry: \"* Histopathologically confirmed rectal adenocarcinoma with no prior antitumor therapy\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07198165","url":"https://clinicaltrials.gov/study/NCT07198165"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07198165","phase":"2","setting":"Short-Course Radiotherapy Combined With CAPOX and Bevacizumab, With or Without PD-1 Inhibitors, as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer","sponsor":"Ruijin Hospital","participation":[{"nct":"NCT07198165","source":"https://clinicaltrials.gov/study/NCT07198165","fetchedAt":"2026-10-07T16:55:32.313Z","studySha256":"01151b84e5ccbeb21c3d1fc2f969638a8d3c7f9f9071e4a6aca962dcbcd95525","overallStatus":"RECRUITING","lastUpdatePosted":"2025-09-30","leadSponsor":"Ruijin Hospital","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":104,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2025-09-05","startedType":"actual","enrolled":104,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07198165/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}