{"entity":{"id":"nct07172919","kind":"trial","name":"A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation","aka":[],"tldr":"A phase 2 trial of Sotorasib and Panitumumab in advanced solid tumours, run by Amgen, now recruiting.","summary":"A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation is a phase 2 interventional study registered as NCT07172919 by Amgen, with 14 participants planned, started 2026-01-02 and due to reach its primary completion in 2028-07-01. Interventions recorded: Sotorasib and Panitumumab.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07172919","url":"https://clinicaltrials.gov/study/NCT07172919"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":["kras-inhibitors","monoclonal-antibody"],"targets":[],"drugs":["sotorasib","panitumumab"],"companies":["amgen"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07172919","phase":"2","setting":"A Rollover Study of Sotorasib With or Without Panitumumab for the Treatment of Cancer Subjects With KRAS p.G12C Mutation Previously Treated in an Amgen-Sponsored Study","sponsor":"Amgen","participation":[{"nct":"NCT07172919","source":"https://clinicaltrials.gov/study/NCT07172919","fetchedAt":"2026-10-07T16:55:29.886Z","studySha256":"50a226ae979f6a75fb5782d369446844ce4870133ba6ac7932b4aafc59d4aed9","overallStatus":"RECRUITING","lastUpdatePosted":"2026-07-23","leadSponsor":"Amgen","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":14,"enrolmentType":"ESTIMATED","siteCount":11,"recruitingSiteCount":9,"countries":["Australia","France","Germany","Greece","Italy","Japan","Switzerland","Taiwan","United States"]}],"started":"2026-01-02","startedType":"actual","enrolled":14,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07172919/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"technology":[{"id":"kras-inhibitors","kind":"technology","name":"KRAS & RAS inhibitors","route":"/technologies/kras-inhibitors/"},{"id":"monoclonal-antibody","kind":"technology","name":"Monoclonal antibodies","route":"/technologies/monoclonal-antibody/"}],"drug":[{"id":"panitumumab","kind":"drug","name":"Panitumumab","route":"/drugs/panitumumab/"},{"id":"sotorasib","kind":"drug","name":"Sotorasib","route":"/drugs/sotorasib/"}],"company":[{"id":"amgen","kind":"company","name":"Amgen","route":"/companies/amgen/"}]}}