{"entity":{"id":"nct07154264","kind":"trial","name":"A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10)","aka":["TAI-SHAN10"],"tldr":"A phase 2 trial of DZD8586 and Venetoclax in chronic lymphocytic leukaemia, run by Dizal Pharmaceuticals, now recruiting.","summary":"A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10) is a phase 2 interventional study registered as NCT07154264 by Dizal Pharmaceuticals, with 66 participants planned, started 2025-09-22 and due to reach its primary completion in 2029-12. Interventions recorded: DZD8586 and Venetoclax.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07154264","url":"https://clinicaltrials.gov/study/NCT07154264"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["cll"],"sections":[],"technologies":[],"targets":[],"drugs":["dzd8586","venetoclax"],"companies":["dizal"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07154264","phase":"2","setting":"A Phase 2 Study of DZD8586 Combination Therapy in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (CLL/SLL)","sponsor":"Dizal Pharmaceuticals","participation":[{"nct":"NCT07154264","source":"https://clinicaltrials.gov/study/NCT07154264","fetchedAt":"2026-10-07T16:55:29.886Z","studySha256":"ae74601f3b1c8e45f33a6114ef8e3a411f2a49e1dd667c17e07246763207350b","overallStatus":"RECRUITING","lastUpdatePosted":"2026-06-22","leadSponsor":"Dizal Pharmaceuticals","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":66,"enrolmentType":"ESTIMATED","siteCount":15,"recruitingSiteCount":14,"countries":["China"]}],"started":"2025-09-22","startedType":"actual","enrolled":66,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07154264/","neighbours":{"cancer":[{"id":"cll","kind":"cancer","name":"Chronic lymphocytic leukaemia","route":"/cancers/cll/"}],"drug":[{"id":"dzd8586","kind":"drug","name":"DZD8586","route":"/drugs/dzd8586/"},{"id":"venetoclax","kind":"drug","name":"Venetoclax","route":"/drugs/venetoclax/"}],"company":[{"id":"dizal","kind":"company","name":"Dizal Pharmaceutical","route":"/companies/dizal/"}]}}