{"entity":{"id":"nct07095309","kind":"trial","name":"Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal Cancer","aka":["NeoART-M"],"tldr":"A phase 2 trial in colorectal cancer, run by Metanoic Health Ltd., not yet recruiting.","summary":"Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/ III Colorectal Cancer is a phase 2, randomised interventional study registered as NCT07095309 by Metanoic Health Ltd., with a registry enrolment figure of 120 participants, started 2025-08-15 and due to reach its primary completion in 2032-08-30. Interventions recorded: Artesunate; Artesunate matching Placebo. Conditions listed: Stage II/III Colon Cancer; Bowel Cancer. Primary outcome: Recurrence-Free Survival (RFS) at 2 Years Post-Randomisation Assessed by Radiological and Clinical Evaluation. Colorectal eligibility wording from the registry: \"* Histologically proven single primary site colorectal adenocarcinoma or high grade dysplasia plus unequivocal radiological evidence of invasive cancer\". Sites: Malaysia. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT07095309","url":"https://clinicaltrials.gov/study/NCT07095309"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07095309","phase":"2","setting":"Phase II Randomised, Double Blind, Placebo Controlled Trial of Neoadjuvant Artesunate in Stage II/III Colorectal Cancer","sponsor":"Metanoic Health Ltd.","participation":[{"nct":"NCT07095309","source":"https://clinicaltrials.gov/study/NCT07095309","fetchedAt":"2026-10-07T16:55:25.997Z","studySha256":"2444d52e91f01f4844b4b4405b80572d570b633681889cb52649081228f51089","overallStatus":"NOT_YET_RECRUITING","lastUpdatePosted":"2025-07-31","leadSponsor":"Metanoic Health Ltd.","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":120,"enrolmentType":"ESTIMATED","siteCount":6,"recruitingSiteCount":0,"countries":["Malaysia"]}],"started":"2025-08-15","startedType":"estimated","enrolled":120,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07095309/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}