{"entity":{"id":"nct07079228","kind":"trial","name":"A Study to Compare QLS31905 and Chemotherapy With Placebo and Chemotherapy in Participants With Pancreatic Cancer","aka":[],"tldr":"A phase 3 trial testing QLS31905 in pancreatic ductal adenocarcinoma, now recruiting.","summary":"A Study to Compare QLS31905 and Chemotherapy With Placebo and Chemotherapy in Participants With Pancreatic Cancer is a phase 3 interventional study registered as NCT07079228, led by Qilu Pharmaceutical, and recruiting on the registry. Official title: A Phase 3, Multi-Center, Double-blind, Randomised Study of QLS31905 Plus Chemotherapy Versus Placebo Plus Chemotherapy as First-Line Treatment in Participants With Claudin (CLDN)18.2-Positive Advanced Pancreatic Cancer. Planned enrolment is 602 participants (estimated). The study started in 2025-09-08 and primary completion is expected in 2028-12. No results have been posted on ClinicalTrials.gov.","status":"recruiting","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT07079228","url":"https://clinicaltrials.gov/study/NCT07079228"}],"tags":["ctgov-ingest"],"related":[],"cancers":["pancreatic","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":["qls31905"],"companies":["qilu-pharmaceutical"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07079228","phase":"3","setting":"A Phase 3, Multi-Center, Double-blind, Randomized Study of QLS31905 Plus Chemotherapy Versus Placebo Plus Chemotherapy as First-Line Treatment in Participants With Claudin (CLDN)18.2-Positive Advanced Pancreatic Cancer","sponsor":"Qilu Pharmaceutical","participation":[{"nct":"NCT07079228","source":"https://clinicaltrials.gov/study/NCT07079228","fetchedAt":"2026-10-07T16:55:25.997Z","studySha256":"cab8877f8d8af3bfe02664bb1a7909e05751f1685a9d5afcccd5e3180a2233d3","overallStatus":"RECRUITING","lastUpdatePosted":"2025-09-23","leadSponsor":"Qilu Pharmaceutical Co., Ltd.","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":602,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2025-09-08","startedType":"actual","enrolled":602,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07079228/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"drug":[{"id":"qls31905","kind":"drug","name":"QLS31905","route":"/drugs/qls31905/"}],"company":[{"id":"qilu-pharmaceutical","kind":"company","name":"Qilu Pharmaceutical","route":"/companies/qilu-pharmaceutical/"}]}}