{"entity":{"id":"nct07022002","kind":"trial","name":"SSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid Tumors","aka":[],"tldr":"A phase 2 trial of SSGJ-705 in advanced solid tumours, run by Shenyang Sunshine Pharmaceutical Co., LTD., now recruiting.","summary":"SSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid Tumors is a phase 2 interventional study registered as NCT07022002 by Shenyang Sunshine Pharmaceutical Co., LTD., with 340 participants planned, started 2025-07-30 and due to reach its primary completion in 2026-12-31. Interventions recorded: SSGJ-705, PD-1/L1 inhibitor combined with chemotherapy and SSGJ-705 combined with chemotherapy.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT07022002","url":"https://clinicaltrials.gov/study/NCT07022002"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["ssgj-705"],"companies":["3sbio"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07022002","phase":"2","setting":"A Phase II Study to Evaluate the Safety and Efficacy of SSGJ-705 Monotherapy and Combination Therapy in Patients With Advanced HER2-Expressing Solid Tumors","sponsor":"Shenyang Sunshine Pharmaceutical Co., LTD.","participation":[{"nct":"NCT07022002","source":"https://clinicaltrials.gov/study/NCT07022002","fetchedAt":"2026-10-07T16:55:21.080Z","studySha256":"38f43f640b2296282e84ad4e5d3aec0276cbf52d728d17fc815838e98e77b84f","overallStatus":"RECRUITING","lastUpdatePosted":"2025-08-03","leadSponsor":"Shenyang Sunshine Pharmaceutical Co., LTD.","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":340,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2025-07-30","startedType":"actual","enrolled":340,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07022002/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"ssgj-705","kind":"drug","name":"SSGJ-705","route":"/drugs/ssgj-705/"}],"company":[{"id":"3sbio","kind":"company","name":"3SBio","route":"/companies/3sbio/"}]}}