{"entity":{"id":"nct07015892","kind":"trial","name":"Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial","aka":["ESCALADOR"],"tldr":"A phase 3 trial in lung cancer, run by Instituto de Investigación Biomédica de Salamanca, now recruiting.","summary":"Dose-Escalation Radiotherapy in Limited-Stage Small Cell Lung Cancer: A Phase III Randomized Trial is a phase 3, randomised interventional study registered as NCT07015892 by Instituto de Investigación Biomédica de Salamanca, with a registry enrolment figure of 300 participants, started 2026-03-01 and due to reach its primary completion in 2028-09-01. Interventions recorded: Thoracic Radiotherapy 45 Gy BID; Thoracic Radiotherapy 60 Gy BID; Thoracic Radiotherapy SIB 45-54 Gy BID. Conditions listed: Small Cell Lung Carcinoma. Primary outcome: Progression-Free Survival (PFS). Lung eligibility wording from the registry: \"* Histologically confirmed diagnosis of small cell lung cancer (SCLC)\". Sites: Spain. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT07015892","url":"https://clinicaltrials.gov/study/NCT07015892"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["limited-stage-sclc"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07015892","phase":"3","setting":"Phase III Randomized Clinical Trial to Evaluate the Efficacy and Safety of Twice-Daily Hyperfractionated Dose-Escalated Thoracic Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer (ESCALADOR Study)","sponsor":"Instituto de Investigación Biomédica de Salamanca","participation":[{"nct":"NCT07015892","source":"https://clinicaltrials.gov/study/NCT07015892","fetchedAt":"2026-10-07T16:55:21.080Z","studySha256":"a0698fd24b175053e3b78d570741a346d4881e2a5e80dd30d8623c018f59aa65","overallStatus":"RECRUITING","lastUpdatePosted":"2026-03-31","leadSponsor":"Instituto de Investigación Biomédica de Salamanca","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":300,"enrolmentType":"ESTIMATED","siteCount":13,"recruitingSiteCount":3,"countries":["Spain"]}],"started":"2026-03-01","startedType":"actual","enrolled":300,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07015892/","neighbours":{"cancer":[{"id":"limited-stage-sclc","kind":"cancer","name":"Limited-stage small-cell lung cancer","route":"/cancers/limited-stage-sclc/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}