{"entity":{"id":"nct06938321","kind":"trial","name":"A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer","aka":[],"tldr":"A phase 1/2 trial of AK112 in biliary tract cancer, run by Akeso, now recruiting.","summary":"A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer is a phase 1/2 interventional study registered as NCT06938321 by Akeso, with 135 participants planned, started 2025-04-30 and due to reach its primary completion in 2027-05. Interventions recorded: AK112 and AK130.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06938321","url":"https://clinicaltrials.gov/study/NCT06938321"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["cholangiocarcinoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["akeso"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06938321","phase":"1/2","setting":"An Open Label, Multicenter, Phase Ib/II Clinical Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer","sponsor":"Akeso","participation":[{"nct":"NCT06938321","source":"https://clinicaltrials.gov/study/NCT06938321","fetchedAt":"2026-10-07T16:55:18.467Z","studySha256":"1e47a34bc23d56996c6cf2228344bcaa4b82c2da6ff7066b4dcedcc1a27c9c14","overallStatus":"RECRUITING","lastUpdatePosted":"2026-03-03","leadSponsor":"Akeso","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":135,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2025-04-30","startedType":"actual","enrolled":135,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06938321/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"}],"company":[{"id":"akeso","kind":"company","name":"Akeso","route":"/companies/akeso/"}]}}