{"entity":{"id":"nct06929663","kind":"trial","name":"A Study of AK146D1 for Injection in the Treatment of Advanced Solid Tumors","aka":[],"tldr":"An early trial studying the safety and activity of experimental treatment. Its registry status does not establish patient benefit.","summary":"A Study of AK146D1 for Injection in the Treatment of Advanced Solid Tumors. ClinicalTrials.gov record last updated 2025-07-17: recruiting. Enrollment is planned at 48 participants. Primary completion is estimated at 2026-11-05. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications.","status":"recruiting","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT06929663","url":"https://clinicaltrials.gov/study/NCT06929663"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":["trop2"],"drugs":["ak146d1"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["ClinicalTrials.gov record last updated 2025-07-17: recruiting. Enrollment is planned at 48 participants. Primary completion is estimated at 2026-11-05. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications."],"nct":"NCT06929663","phase":"1","setting":"A Study of AK146D1 for Injection in the Treatment of Advanced Solid Tumors","sponsor":"Akeso","participation":[{"nct":"NCT06929663","source":"https://clinicaltrials.gov/study/NCT06929663","fetchedAt":"2026-10-08T16:42:13.801Z","studySha256":"54f995e76746b0e901fb833219565fd24c833599f493ceb2e40be77dda5de399","overallStatus":"RECRUITING","lastUpdatePosted":"2025-07-17","leadSponsor":"Akeso","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":48,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["Australia"]}],"started":"2025-07-02","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06929663/","neighbours":{"target":[{"id":"trop2","kind":"target","name":"TROP2","route":"/targets/trop2/"}],"drug":[{"id":"ak146d1","kind":"drug","name":"AK146D1","route":"/drugs/ak146d1/"}]}}