{"entity":{"id":"nct06922383","kind":"trial","name":"A Clinical Study of Arfolitixorin in Patients With mCRC","aka":[],"tldr":"A phase 1/2 trial of Arfolitixorin in colorectal cancer, run by Isofol Medical AB, now recruiting.","summary":"A Clinical Study of Arfolitixorin in Patients With mCRC is a phase 1/2 interventional study registered as NCT06922383 by Isofol Medical AB, with 90 participants planned, started 2025-04-10 and due to reach its primary completion in 2028-11-30. Interventions recorded: Arfolitixorin.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06922383","url":"https://clinicaltrials.gov/study/NCT06922383"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["colorectal"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["fluorouracil"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06922383","phase":"1/2","setting":"A Phase 1b/2 Study of Arfolitixorin as Part of 5-fluorouracil-based Treatment Regimens in the First-line Treatment of Metastatic Colorectal Cancer","sponsor":"Isofol Medical AB","participation":[{"nct":"NCT06922383","source":"https://clinicaltrials.gov/study/NCT06922383","fetchedAt":"2026-10-07T16:55:18.467Z","studySha256":"46372ccec99908085f755dbf19d1f8d28200c5e68989a2383ee06cf8cd50d989","overallStatus":"RECRUITING","lastUpdatePosted":"2026-06-29","leadSponsor":"Isofol Medical AB","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":90,"enrolmentType":"ESTIMATED","siteCount":3,"recruitingSiteCount":1,"countries":["Germany"]}],"started":"2025-04-10","startedType":"actual","enrolled":90,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06922383/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"fluorouracil","kind":"drug","name":"Fluorouracil (5-FU)","route":"/drugs/fluorouracil/"}]}}