{"entity":{"id":"nct06907615","kind":"trial","name":"A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)","aka":[],"tldr":"A phase 2 trial of HLX43 DOSE 1 (2.0 mg/kg) in non-small-cell lung cancer, run by Shanghai Henlius Biotech, now recruiting.","summary":"A Phase II Clinical Study to Evaluate HLX43 in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC) is a phase 2 interventional study registered as NCT06907615 by Shanghai Henlius Biotech, with 243 participants planned, started 2025-06-09 and due to reach its primary completion in 2028-04-20. Interventions recorded: HLX43 DOSE 1 (2.0 mg/kg) and HLX43 DOSE 2 (2.5 mg/kg).","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06907615","url":"https://clinicaltrials.gov/study/NCT06907615"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["henlius"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06907615","phase":"2","setting":"An Open-label, Multi-center, Global Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX43 (Anti-PD-L1 ADC) in Subjects With Advanced Non-small Cell Lung Cancer (NSCLC)","sponsor":"Shanghai Henlius Biotech","participation":[{"nct":"NCT06907615","source":"https://clinicaltrials.gov/study/NCT06907615","fetchedAt":"2026-10-07T16:55:17.578Z","studySha256":"552378ec1b761e8f7b93d77ea926b16d3e3649800847a0fb34194c2a82964f59","overallStatus":"RECRUITING","lastUpdatePosted":"2026-10-01","leadSponsor":"Shanghai Henlius Biotech","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":243,"enrolmentType":"ESTIMATED","siteCount":2,"recruitingSiteCount":2,"countries":["China","United States"]}],"started":"2025-06-09","startedType":"actual","enrolled":243,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06907615/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"company":[{"id":"henlius","kind":"company","name":"Shanghai Henlius Biotech","route":"/companies/henlius/"}]}}