{"entity":{"id":"nct06808412","kind":"trial","name":"To Explore the Efficacy of Sintilimab Combined With Bevacizumab in Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by xiaohua li, now recruiting.","summary":"To Explore the Efficacy of Sintilimab Combined With Bevacizumab in Rectal Cancer is a phase 2, interventional study registered as NCT06808412 by xiaohua li, with a registry enrolment figure of 118 participants, started 2024-07-05 and due to reach its primary completion in 2025-05-05. Interventions recorded: sintilimab combined with bevacizumab and XELOX. Conditions listed: Rcctal Cancer. Primary outcome: assess the pathological complete response (pCR) rate of tumors after neoadjuvant chemotherapy for rectal cancer using sintilimab combined with bevacizumab. Colorectal eligibility wording from the registry: \"Rectal cancer patients who have previously received perioperative XELOX regimen treatment\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06808412","url":"https://clinicaltrials.gov/study/NCT06808412"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06808412","phase":"2","setting":"A Study on the Efficacy and Safety of Sintilimab Combined With Bevacizumab in Perioperative Neoadjuvant Chemotherapy for Locally Advanced Low Rectal Cancer","sponsor":"xiaohua li","participation":[{"nct":"NCT06808412","source":"https://clinicaltrials.gov/study/NCT06808412","fetchedAt":"2026-10-07T16:55:06.589Z","studySha256":"b0cbdccf3197b36f2e6b285a34a5a233570015792d651a5d27de81327e006159","overallStatus":"RECRUITING","lastUpdatePosted":"2025-02-05","leadSponsor":"xiaohua li","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"75 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":118,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2024-07-05","startedType":"actual","enrolled":118,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06808412/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}