{"entity":{"id":"nct06765616","kind":"trial","name":"Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Feng Tian, now recruiting.","summary":"Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer is a phase 2, interventional study registered as NCT06765616 by Feng Tian, with a registry enrolment figure of 31 participants, started 2024-01-01 and due to reach its primary completion in 2025-07-01. Interventions recorded: Adebrelimab Injection combined with radiotherapy and chemotherapy. Conditions listed: Rectal Cancer; Advanced Stage Colorectal Cancer; Radiotherapy. Primary outcome: Pathological complete remission rate (pCR). Colorectal eligibility wording from the registry: \"Patients diagnosed with rectal adenocarcinoma through primary lesion biopsy and histopathological examination;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06765616","url":"https://clinicaltrials.gov/study/NCT06765616"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06765616","phase":"2","setting":"Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer: a Multicenter, Single Arm Prospective Study","sponsor":"Feng Tian","participation":[{"nct":"NCT06765616","source":"https://clinicaltrials.gov/study/NCT06765616","fetchedAt":"2026-10-07T16:55:00.061Z","studySha256":"55bbb8f8b0a8d320a9a103326dc8ae9df5cd9b1a1fabb74d5a6b25104b5baa60","overallStatus":"RECRUITING","lastUpdatePosted":"2025-01-09","leadSponsor":"Feng Tian","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"85 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":31,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2024-01-01","startedType":"actual","enrolled":31,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06765616/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}