{"entity":{"id":"nct06689163","kind":"trial","name":"A Study for the Treatment of Metastatic Prostate Cancer With HRS-1167 Tablets Combined With Abiraterone Acetate Tablets and Prednisone","aka":[],"tldr":"This study tests a PARP inhibitor; the registry reports that it is recruiting.","summary":"The registry lists NCT06689163 as recruiting, last updated 2025-09-03. Enrolment is 66 planned participants, an estimate. Interventions: HRS-1167 tablets, Abiraterone Acetate tablets（II）, Prednisone Acetate tablets. Primary measures include Dose limiting toxicity (DLT); Recommended phase II dose (RP2D). No results are posted in the registry; this does not exclude separate publications.","status":"recruiting","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT06689163","url":"https://clinicaltrials.gov/study/NCT06689163"}],"tags":["ctgov-ingest"],"related":[],"cancers":["prostate"],"sections":[],"technologies":[],"targets":["parp"],"drugs":["prednisone","hrs-1167"],"companies":["hengrui"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06689163","phase":"1/2","setting":"An Open, Multicenter Phase Ib/II Study for the Treatment of Metastatic Prostate Cancer With HRS-1167 Tablets Combined With Abiraterone Acetate Tablets and Prednisone","sponsor":"Jiangsu HengRui Medicine Co., Ltd.","participation":[{"nct":"NCT06689163","source":"https://clinicaltrials.gov/study/NCT06689163","fetchedAt":"2026-10-07T16:54:56.691Z","studySha256":"a842f03e8a78c6549b6ae20f7e7b833711730a225bfc0c01c8be3033ecef19e7","overallStatus":"RECRUITING","lastUpdatePosted":"2025-09-03","leadSponsor":"Jiangsu HengRui Medicine Co., Ltd.","collaboratorCount":0,"minimumAge":"18 Years","sex":"MALE","healthyVolunteers":false,"hasEligibility":true,"enrolment":66,"enrolmentType":"ESTIMATED","siteCount":2,"recruitingSiteCount":2,"countries":["China"]}],"started":"2024-12-11","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06689163/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"target":[{"id":"parp","kind":"target","name":"PARP","route":"/targets/parp/"}],"drug":[{"id":"hrs-1167","kind":"drug","name":"HRS-1167","route":"/drugs/hrs-1167/"},{"id":"prednisone","kind":"drug","name":"Prednisone","route":"/drugs/prednisone/"}],"company":[{"id":"hengrui","kind":"company","name":"Jiangsu Hengrui Pharmaceuticals","route":"/companies/hengrui/"}]}}