{"entity":{"id":"nct06634849","kind":"trial","name":"An Open Label Dose Finding Study of PTT-4256 in Patients With Solid Tumours (RAISIC-1).","aka":["RAISIC-1"],"tldr":"A phase 1/2 trial of PTT-4256 in advanced solid tumours, run by Pathios Therapeutics Pty Ltd, now recruiting.","summary":"An Open Label Dose Finding Study of PTT-4256 in Patients With Solid Tumours (RAISIC-1). is a phase 1/2 interventional study registered as NCT06634849 by Pathios Therapeutics Pty Ltd, with 30 participants planned, started 2024-11-04 and due to reach its primary completion in 2027-04-30. Interventions recorded: PTT-4256.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06634849","url":"https://clinicaltrials.gov/study/NCT06634849"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06634849","phase":"1/2","setting":"A Modular, Open Label, Dose Finding, Phase 1/2 Clinical Trial in Patients With Solid Tumours to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of PTT-4256.","sponsor":"Pathios Therapeutics Pty Ltd","participation":[{"nct":"NCT06634849","source":"https://clinicaltrials.gov/study/NCT06634849","fetchedAt":"2026-10-07T16:54:53.335Z","studySha256":"e643f26a367d73338840ca75fd7c3904f20816cbced304c894414549a0efeb6d","overallStatus":"RECRUITING","lastUpdatePosted":"2026-02-10","leadSponsor":"Pathios Therapeutics Pty Ltd","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":30,"enrolmentType":"ESTIMATED","siteCount":5,"recruitingSiteCount":5,"countries":["Australia"]}],"started":"2024-11-04","startedType":"actual","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06634849/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}]}}