{"entity":{"id":"nct06523673","kind":"trial","name":"Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer","aka":["OPPRESS"],"tldr":"A phase 3 trial in lung cancer, run by Second Affiliated Hospital, Zhejiang University, School of Medicine, now recruiting.","summary":"Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer is a phase 3, randomised interventional study registered as NCT06523673 by Second Affiliated Hospital, Zhejiang University, School of Medicine, with a registry enrolment figure of 104 participants, started 2024-09 and due to reach its primary completion in 2027-09. Interventions recorded: Stereotactic Body Radiotherapy; second-line systemic therapy. Conditions listed: Metastatic Non-Small Cell Lung Cancer; NSCLC Stage IV; OligoProgressive Metastatic Disease. Primary outcome: progression-free survival (PFS). Lung eligibility wording from the registry: \"* Histologically and/or cytologically confirmed stage IV metastatic NSCLC\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT06523673","url":"https://clinicaltrials.gov/study/NCT06523673"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":["sbrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06523673","phase":"3","setting":"Stereotactic Body Radiotherapy (SBRT) for Oligo-Progression During First-Line Chemotherapy in Metastatic Non-Small Cell Lung Cancer (OPPRESS):A Randomized, Controlled, Open-label, Multi-Center Phase 3 Study","sponsor":"Second Affiliated Hospital, Zhejiang University, School of Medicine","participation":[{"nct":"NCT06523673","source":"https://clinicaltrials.gov/study/NCT06523673","fetchedAt":"2026-10-07T16:54:46.480Z","studySha256":"ef62bd042efef32e8877043861da41c601f573f5526b6c6cd12809c66511b13f","overallStatus":"RECRUITING","lastUpdatePosted":"2024-08-30","leadSponsor":"Second Affiliated Hospital, Zhejiang University, School of Medicine","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":104,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["China"]}],"started":"2024-09","startedType":"estimated","enrolled":104,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06523673/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}