{"entity":{"id":"nct06380660","kind":"trial","name":"Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of ACE-86225106 tablet in ovarian cancer and prostate cancer, run by Acerand Therapeutics (Shanghai) Limited, active and no longer recruiting.","summary":"Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06380660 by Acerand Therapeutics (Shanghai) Limited, with 298 participants enrolled, started 2024-03-22 and due to reach its primary completion in 2028-12-21. Interventions recorded: ACE-86225106 tablet.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06380660","url":"https://clinicaltrials.gov/study/NCT06380660"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["ovarian","prostate"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06380660","phase":"1/2","setting":"A Phase I/II, Open-label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Ascending Doses of ACE-86225106 as Monotherapy in Patients With Advanced Solid Tumors","sponsor":"Acerand Therapeutics (Shanghai) Limited","participation":[{"nct":"NCT06380660","source":"https://clinicaltrials.gov/study/NCT06380660","fetchedAt":"2026-10-07T16:54:36.402Z","studySha256":"09e64b61d4a817dcf9df8c28fce77cd02f18af57eadd5941bc53dcfcf00ad289","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-08-04","leadSponsor":"Acerand Therapeutics (Shanghai) Limited","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":298,"enrolmentType":"ESTIMATED","siteCount":14,"recruitingSiteCount":0,"countries":["China"]}],"started":"2024-03-22","startedType":"actual","enrolled":298,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06380660/","neighbours":{"cancer":[{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}]}}