{"entity":{"id":"nct06118086","kind":"trial","name":"Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma","aka":[],"tldr":"A phase 1/2 trial of REM-422 in salivary gland cancers, run by Remix Therapeutics, now recruiting.","summary":"Study of REM-422 in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma is a phase 1/2 interventional study registered as NCT06118086 by Remix Therapeutics, with 125 participants planned, started 2023-12-20 and due to reach its primary completion in 2027-09-30. Interventions recorded: REM-422.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06118086","url":"https://clinicaltrials.gov/study/NCT06118086"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["salivary-gland","adenoid-cystic-carcinoma"],"sections":[],"technologies":[],"targets":[],"drugs":["rem-422"],"companies":["remix-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06118086","phase":"1/2","setting":"A Phase 1/2, Multicenter, Open-label Study of REM-422, a MYB mRNA Degrader, in Patients With Recurrent, Metastatic, or Unresectable Adenoid Cystic Carcinoma","sponsor":"Remix Therapeutics","participation":[{"nct":"NCT06118086","source":"https://clinicaltrials.gov/study/NCT06118086","fetchedAt":"2026-10-07T16:54:14.819Z","studySha256":"a019e8027200a8efdf2ff974c1eecd9671b1d7f32a452c8915792d072cf58db1","overallStatus":"RECRUITING","lastUpdatePosted":"2026-06-24","leadSponsor":"Remix Therapeutics","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":125,"enrolmentType":"ESTIMATED","siteCount":9,"recruitingSiteCount":9,"countries":["France","United States"]}],"started":"2023-12-20","startedType":"actual","enrolled":125,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06118086/","neighbours":{"cancer":[{"id":"adenoid-cystic-carcinoma","kind":"cancer","name":"Adenoid cystic carcinoma","route":"/cancers/adenoid-cystic-carcinoma/"},{"id":"salivary-gland","kind":"cancer","name":"Salivary gland cancers","route":"/cancers/salivary-gland/"}],"drug":[{"id":"rem-422","kind":"drug","name":"REM-422","route":"/drugs/rem-422/"}],"company":[{"id":"remix-therapeutics","kind":"company","name":"Remix Therapeutics","route":"/companies/remix-therapeutics/"}]}}