{"entity":{"id":"nct05939687","kind":"trial","name":"Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection","aka":["ProMeLAR"],"tldr":"A phase 3 trial in colorectal cancer, run by Blokhin's Russian Cancer Research Center, now recruiting.","summary":"Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection is a phase 3, randomised interventional study registered as NCT05939687 by Blokhin's Russian Cancer Research Center, with a registry enrolment figure of 142 participants, started 2023-06-05 and due to reach its primary completion in 2028-12-01. Interventions recorded: mesh; non-mesh. Conditions listed: Neoplasms Malignant; Rectal Cancer; Hernia Incisional; Surgery. Primary outcome: hernia rate. Colorectal eligibility wording from the registry: \"* Integrity of colorectal anastomosis\". Sites: Russia. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05939687","url":"https://clinicaltrials.gov/study/NCT05939687"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05939687","phase":"3","setting":"Prophylactic Mesh Placement During Temporary Stoma Closure: a Prospective Randomized Phase III Clinical Trial","sponsor":"Blokhin's Russian Cancer Research Center","participation":[{"nct":"NCT05939687","source":"https://clinicaltrials.gov/study/NCT05939687","fetchedAt":"2026-10-07T16:54:02.117Z","studySha256":"2ca07c6fe65385ec8725000d9d27cae3256dc757674bad425e83caa6973c21d7","overallStatus":"RECRUITING","lastUpdatePosted":"2024-08-07","leadSponsor":"Blokhin's Russian Cancer Research Center","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"85 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":142,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["Russia"]}],"started":"2023-06-05","startedType":"actual","enrolled":142,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05939687/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}