{"entity":{"id":"nct05862285","kind":"trial","name":"A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study","aka":["UmbrellaMAX"],"tldr":"A phase 3 trial testing Ipatasertib, now recruiting.","summary":"A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study is a phase 3 interventional study registered as NCT05862285, led by Hoffmann-La Roche, and recruiting on the registry. Official title: An Open-Label, Multicenter Extension Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Study. Planned enrolment is 100 participants (estimated). The study started in 2023-06-01 and primary completion is expected in 2033-03-01. No results have been posted on ClinicalTrials.gov.","status":"recruiting","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT05862285","url":"https://clinicaltrials.gov/study/NCT05862285"}],"tags":["ctgov-ingest"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":["ipatasertib"],"companies":["roche-genentech"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05862285","phase":"3","setting":"An Open-Label, Multicenter Extension Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Study","sponsor":"Hoffmann-La Roche","participation":[{"nct":"NCT05862285","source":"https://clinicaltrials.gov/study/NCT05862285","fetchedAt":"2026-10-07T16:53:58.081Z","studySha256":"c63a02e5e84b7bdfe525bfa7f6851060c15e7b76c389e618c9d0db51ea5d9e53","overallStatus":"RECRUITING","lastUpdatePosted":"2026-10-02","leadSponsor":"Hoffmann-La Roche","collaboratorCount":0,"sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":100,"enrolmentType":"ESTIMATED","siteCount":77,"recruitingSiteCount":59,"countries":["Belgium","Canada","China","Costa Rica","France","Greece","Japan","Mexico","Poland","Russia","South Korea","Taiwan","Thailand","Ukraine","United Kingdom"]}],"started":"2023-06-01","startedType":"actual","enrolled":100,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05862285/","neighbours":{"drug":[{"id":"ipatasertib","kind":"drug","name":"Ipatasertib","route":"/drugs/ipatasertib/"}],"company":[{"id":"roche-genentech","kind":"company","name":"Roche / Genentech","route":"/companies/roche-genentech/"}]}}