{"entity":{"id":"nct05806385","kind":"trial","name":"Grouping Immune-modulation With Cryoablation (LOGIC) for Breast Cancers","aka":["LOGIC"],"tldr":"A phase 1/2 trial in triple-negative breast cancer, run by Texas Tech University Health Sciences Center, not yet recruiting.","summary":"Grouping Immune-modulation With Cryoablation (LOGIC) for Breast Cancers is a phase 1/2, randomised interventional study registered as NCT05806385 by Texas Tech University Health Sciences Center, with a registry enrolment figure of 36 participants, started 2026-03 and due to reach its primary completion in 2027-01. Interventions recorded: Cryoablation; Cryoablation combined with PD1 Inhibitor. Conditions listed: Triple Negative Breast Cancer. Triple-negative eligibility wording from the registry: \"* Diagnoses: Invasive carcinoma, ER -, PR-, HER2- (triple negative)\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05806385","url":"https://clinicaltrials.gov/study/NCT05806385"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05806385","phase":"1/2","setting":"Local Therapy Optimization by Grouping Immune-modulation With Cryoablation (LOGIC) for High Risk Breast Cancers","sponsor":"Texas Tech University Health Sciences Center","participation":[{"nct":"NCT05806385","source":"https://clinicaltrials.gov/study/NCT05806385","fetchedAt":"2026-10-07T16:53:56.649Z","studySha256":"e2237e0a6827d45729818b02b3292d815d79512ee784ea223d7835753c7f59f3","overallStatus":"NOT_YET_RECRUITING","lastUpdatePosted":"2025-09-09","leadSponsor":"Texas Tech University Health Sciences Center","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"90 Years","sex":"FEMALE","healthyVolunteers":false,"hasEligibility":true,"enrolment":36,"enrolmentType":"ESTIMATED","siteCount":0,"recruitingSiteCount":0}],"started":"2026-03","startedType":"estimated","enrolled":36,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05806385/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}