{"entity":{"id":"nct05579132","kind":"trial","name":"A Clinical Study of MK-1045 (CN201) in People With Precursor B-cell Acute Lymphoblastic Leukemia (MK-1045-002)","aka":[],"tldr":"A phase 1/2 trial of MK-1045 in acute lymphoblastic leukaemia, run by MSD R&D (China) Co., Ltd., now recruiting.","summary":"A Clinical Study of MK-1045 (CN201) in People With Precursor B-cell Acute Lymphoblastic Leukemia (MK-1045-002) is a phase 1/2 interventional study registered as NCT05579132 by MSD R&D (China) Co., Ltd., with 203 participants planned, started 2022-11-01 and due to reach its primary completion in 2028-12-31. Interventions recorded: MK-1045.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05579132","url":"https://clinicaltrials.gov/study/NCT05579132"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["all-leukemia"],"sections":[],"technologies":[],"targets":[],"drugs":["mk-1045"],"companies":["merck"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05579132","phase":"1/2","setting":"An Open-label, Multi-center Phase Ib/II Study of MK-1045 (CN201) in Subjects With Precursor B-cell Acute Lymphoblastic Leukemia","sponsor":"MSD R&D (China) Co., Ltd.","participation":[{"nct":"NCT05579132","source":"https://clinicaltrials.gov/study/NCT05579132","fetchedAt":"2026-10-07T16:53:46.156Z","studySha256":"ab8e31bfefe41f6ab582e4d5eb49a643bd541fd8f00158343d02af5611a06f9a","overallStatus":"RECRUITING","lastUpdatePosted":"2026-08-20","leadSponsor":"MSD R&D (China) Co., Ltd.","collaboratorCount":0,"minimumAge":"2 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":203,"enrolmentType":"ESTIMATED","siteCount":11,"recruitingSiteCount":8,"countries":["China"]}],"started":"2022-11-01","startedType":"actual","enrolled":203,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05579132/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"}],"drug":[{"id":"mk-1045","kind":"drug","name":"MK-1045","route":"/drugs/mk-1045/"}],"company":[{"id":"merck","kind":"company","name":"Merck & Co. (MSD)","route":"/companies/merck/"}]}}