{"entity":{"id":"nct05491525","kind":"trial","name":"Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC","aka":["KANGUROO"],"tldr":"A phase 2/3 trial of Vibegron in childhood cancers, run by Urovant Sciences GmbH, now recruiting.","summary":"Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC is a phase 2/3 interventional study registered as NCT05491525 by Urovant Sciences GmbH, with 71 participants planned, started 2022-10-12 and due to reach its primary completion in 2030-03. Interventions recorded: Vibegron.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05491525","url":"https://clinicaltrials.gov/study/NCT05491525"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["childhood-cancers"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05491525","phase":"2/3","setting":"A Phase 2/3, Open-label, Baseline-controlled, Multicenter, Long-term Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With Neurogenic Detrusor Overactivity (NDO) on Clean Intermittent Catheterization (CIC)","sponsor":"Urovant Sciences GmbH","participation":[{"nct":"NCT05491525","source":"https://clinicaltrials.gov/study/NCT05491525","fetchedAt":"2026-10-07T16:53:43.406Z","studySha256":"cf051d080a01235a21886349067eb5ee1758ccfe4166db406bb6be18ad442126","overallStatus":"RECRUITING","lastUpdatePosted":"2026-06-15","leadSponsor":"Urovant Sciences GmbH","collaboratorCount":1,"minimumAge":"2 Years","maximumAge":"17 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":71,"enrolmentType":"ESTIMATED","siteCount":38,"recruitingSiteCount":32,"countries":["Belgium","Canada","Croatia","Denmark","Georgia","Jordan","Latvia","Lithuania","Malaysia","Philippines","Poland","Romania","Serbia","Slovakia","Turkey (Türkiye)","United States"]}],"started":"2022-10-12","startedType":"actual","enrolled":71,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05491525/","neighbours":{"cancer":[{"id":"childhood-cancers","kind":"cancer","name":"Childhood cancers (all types)","route":"/cancers/childhood-cancers/"}],"target":[{"id":"cic","kind":"target","name":"CIC","route":"/targets/cic/"}]}}