{"entity":{"id":"nct05417321","kind":"trial","name":"A Study Evaluating the Safety and Efficacy of HB0036 in Subjects With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of HB0036 in non-small-cell lung cancer, run by Shanghai Huaota Biopharmaceutical Co., Ltd., now recruiting.","summary":"A Study Evaluating the Safety and Efficacy of HB0036 in Subjects With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT05417321 by Shanghai Huaota Biopharmaceutical Co., Ltd., with 80 participants planned, started 2022-08-25 and due to reach its primary completion in 2025-08-01. Interventions recorded: HB0036.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05417321","url":"https://clinicaltrials.gov/study/NCT05417321"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["hb0036"],"companies":["huabo-biopharm"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05417321","phase":"1/2","setting":"A Phase I/II, Open-label, Multicenter Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of HB0036 in Subjects With Advanced Solid Tumors","sponsor":"Shanghai Huaota Biopharmaceutical Co., Ltd.","participation":[{"nct":"NCT05417321","source":"https://clinicaltrials.gov/study/NCT05417321","fetchedAt":"2026-10-07T16:53:41.920Z","studySha256":"99f4ec523e30e7df44eea580f230f46110c787d5e6dbfbac629581bcc7d02c52","overallStatus":"RECRUITING","lastUpdatePosted":"2025-01-03","leadSponsor":"Shanghai Huaota Biopharmaceutical Co., Ltd.","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":80,"enrolmentType":"ESTIMATED","siteCount":4,"recruitingSiteCount":4,"countries":["China","United States"]}],"started":"2022-08-25","startedType":"actual","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05417321/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"hb0036","kind":"drug","name":"HB0036","route":"/drugs/hb0036/"}],"company":[{"id":"huabo-biopharm","kind":"company","name":"Huabo Biopharm","route":"/companies/huabo-biopharm/"}]}}