{"entity":{"id":"nct04858009","kind":"trial","name":"Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis","aka":[],"tldr":"A phase 2 trial of cisplatin and nab-paclitaxel in pancreatic cancer, run by Mayo Clinic, now recruiting.","summary":"Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis is a phase 2, interventional study registered as NCT04858009 by Mayo Clinic, with a registry enrolment figure of 40 participants, started 2024-02-15 and due to reach its primary completion in 2029-07. Interventions recorded: Cisplatin; Hyperthermic Intraperitoneal Chemotherapy; Nab-paclitaxel; Computed Tomography; Magnetic Resonance Imaging; Positron Emission Tomography. Conditions listed: Metastatic Pancreatic Carcinoma; Stage IV Pancreatic Cancer AJCC v8; Metastatic Malignant Neoplasm in the Peritoneum. Primary outcome: Overall survival; Progression-free survival. Pancreatic eligibility wording from the registry: \"* Cytologic or histologic proof of adenocarcinoma of the pancreas\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT04858009","url":"https://clinicaltrials.gov/study/NCT04858009"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["metastatic-pdac"],"sections":[],"technologies":["cytotoxic-chemotherapy","platinum"],"targets":[],"drugs":["cisplatin","nab-paclitaxel"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04858009","phase":"2","setting":"A Phase II Study of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Patients With Pancreatic Cancer and Peritoneal Metastasis","sponsor":"Mayo Clinic","participation":[{"nct":"NCT04858009","source":"https://clinicaltrials.gov/study/NCT04858009","fetchedAt":"2026-10-07T16:53:29.376Z","studySha256":"f1b5ec4faf12c28f2420a5c783f80a1457885fbc6849b53fab157290d786226d","overallStatus":"RECRUITING","lastUpdatePosted":"2026-09-14","leadSponsor":"Mayo Clinic","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"80 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":40,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":1,"countries":["United States"]}],"started":"2024-02-15","startedType":"actual","enrolled":40,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04858009/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"cisplatin","kind":"drug","name":"Cisplatin","route":"/drugs/cisplatin/"},{"id":"nab-paclitaxel","kind":"drug","name":"Nab-paclitaxel","route":"/drugs/nab-paclitaxel/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}