{"entity":{"id":"nct04762069","kind":"trial","name":"A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme","aka":[],"tldr":"A phase 2 trial of Berubicin in glioma & glioblastoma, run by CNS Pharmaceuticals, Inc., active and no longer recruiting.","summary":"A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme is a phase 2 interventional study registered as NCT04762069 by CNS Pharmaceuticals, Inc., with 252 participants enrolled, started 2021-05-18 and due to reach its primary completion in 2026-04-27. Interventions recorded: Berubicin and Lomustine.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT04762069","url":"https://clinicaltrials.gov/study/NCT04762069"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["glioblastoma"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["lomustine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04762069","phase":"2","setting":"A Multicenter, Open-Label Study With a Randomized Control Arm of the Efficacy, Safety, and Pharmacokinetics of Intravenously Infused Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme After Failure of Standard First Line Therapy","sponsor":"CNS Pharmaceuticals, Inc.","participation":[{"nct":"NCT04762069","source":"https://clinicaltrials.gov/study/NCT04762069","fetchedAt":"2026-10-07T16:53:26.644Z","studySha256":"f9fe0e8190fa4b037a8af0544a211fff49fff1d59369b5d9f0d26b508c43bd1e","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-04-15","leadSponsor":"CNS Pharmaceuticals, Inc.","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":252,"enrolmentType":"ACTUAL","siteCount":48,"recruitingSiteCount":0,"countries":["France","Italy","Spain","Switzerland","United States"]}],"started":"2021-05-18","startedType":"actual","enrolled":252,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04762069/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"lomustine","kind":"drug","name":"Lomustine (CCNU)","route":"/drugs/lomustine/"}]}}