{"entity":{"id":"nct04724980","kind":"trial","name":"Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis","aka":[],"tldr":"A phase 1/2 trial of PRGN-2012 - Phase I; Dose Level 1 in rare cancers of childhood, run by Precigen, Inc, active and no longer recruiting.","summary":"Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis is a phase 1/2 interventional study registered as NCT04724980 by Precigen, Inc, with 38 participants enrolled, started 2021-03-16 and due to reach its primary completion in 2024-06-05. Interventions recorded: PRGN-2012 - Phase I; Dose Level 1, PRGN-2012 - Phase I; Dose Level 2 and PRGN-2012 - Phase II; Dose Level 2.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT04724980","url":"https://clinicaltrials.gov/study/NCT04724980"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["rare-childhood-cancers"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["precigen"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04724980","phase":"1/2","setting":"A Phase 1/2 Study of Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis","sponsor":"Precigen, Inc","participation":[{"nct":"NCT04724980","source":"https://clinicaltrials.gov/study/NCT04724980","fetchedAt":"2026-10-07T16:53:25.962Z","studySha256":"8b2b80ca3bea87b4e4c54d5bd13ed16fca53f723616934ebd5376acfb1dd26ad","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2025-06-11","leadSponsor":"Precigen, Inc","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":38,"enrolmentType":"ACTUAL","siteCount":1,"recruitingSiteCount":0,"countries":["United States"]}],"started":"2021-03-16","startedType":"actual","enrolled":38,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04724980/","neighbours":{"cancer":[{"id":"rare-childhood-cancers","kind":"cancer","name":"Rare cancers of childhood (NCI PDQ umbrella)","route":"/cancers/rare-childhood-cancers/"}],"company":[{"id":"precigen","kind":"company","name":"Precigen","route":"/companies/precigen/"}]}}