{"entity":{"id":"nct04634357","kind":"trial","name":"ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma","aka":["ARYA-2"],"tldr":"A phase 1/2 trial of ET140203 T Cells in hepatoblastoma and hepatocellular carcinoma, run by Eureka Therapeutics Inc., now recruiting.","summary":"ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma is a phase 1/2 interventional study registered as NCT04634357 by Eureka Therapeutics Inc., with 12 participants planned, started 2022-07-19 and due to reach its primary completion in 2027-12-31. Interventions recorded: ET140203 T Cells.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT04634357","url":"https://clinicaltrials.gov/study/NCT04634357"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["hepatoblastoma","hcc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["eureka-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04634357","phase":"1/2","setting":"An Open-Label, Dose Escalation, Phase I/II Clinical Trial of ET140203 T Cells in Pediatric Subjects With Relapsed/Refractory Hepatoblastoma (HB), Hepatocellular Neoplasm-Not Otherwise Specified (HCN-NOS), or Hepatocellular Carcinoma (HCC)","sponsor":"Eureka Therapeutics Inc.","participation":[{"nct":"NCT04634357","source":"https://clinicaltrials.gov/study/NCT04634357","fetchedAt":"2026-10-07T16:53:23.898Z","studySha256":"18e71774c04719cd72fc90a04aff8f2641d05d45ac07f620ba8853efa4a5d835","overallStatus":"RECRUITING","lastUpdatePosted":"2026-07-06","leadSponsor":"Eureka Therapeutics Inc.","collaboratorCount":0,"minimumAge":"1 Year","maximumAge":"21 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":12,"enrolmentType":"ESTIMATED","siteCount":4,"recruitingSiteCount":4,"countries":["United States"]}],"started":"2022-07-19","startedType":"actual","enrolled":12,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04634357/","neighbours":{"cancer":[{"id":"hepatoblastoma","kind":"cancer","name":"Hepatoblastoma","route":"/cancers/hepatoblastoma/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"}],"company":[{"id":"eureka-therapeutics","kind":"company","name":"Eureka Therapeutics","route":"/companies/eureka-therapeutics/"}]}}