{"entity":{"id":"nct04536675","kind":"trial","name":"Effect of Perioperative Bronchodilator in COPD Patients Undergoing Lung Cancer Surgery","aka":[],"tldr":"A phase 3 trial in lung cancer, run by Samsung Medical Center, active but no longer recruiting.","summary":"Effect of Perioperative Bronchodilator in COPD Patients Undergoing Lung Cancer Surgery is a phase 3, randomised interventional study registered as NCT04536675 by Samsung Medical Center, with a registry enrolment figure of 204 participants, started 2021-04-01 and due to reach its primary completion in 2026-04-03. Interventions recorded: Vilanterol and Umeclidinium Bromide; Placebo. Conditions listed: Chronic Obstructive Pulmonary Disease; Non Small Cell Lung Cancer. Primary outcome: Difference in post-bronchodilator FEV1 between baseline and 16 weeks post-surgery. Lung eligibility wording from the registry: \"* Subjects of men or female over 40 years of age who are scheduled for curative pulmonary lobectomy due to confirmation (or high suspicion) of non-small cell lung cancer (NSCLC)\". Sites: South Korea. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT04536675","url":"https://clinicaltrials.gov/study/NCT04536675"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["resectable-nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT04536675","phase":"3","setting":"Effect of Perioperative Fixed-dose Dual Bronchodilator Therapy on Post-operative Pulmonary Function Among Mild- to -Moderate COPD Patients Undergoing Lung Cancer Surgery","sponsor":"Samsung Medical Center","participation":[{"nct":"NCT04536675","source":"https://clinicaltrials.gov/study/NCT04536675","fetchedAt":"2026-10-07T16:53:21.850Z","studySha256":"4887fe80fcccb9206ffb9117ae97bd84532f4922a07982ecce02fb13ad5a99a3","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-06-26","leadSponsor":"Samsung Medical Center","collaboratorCount":0,"minimumAge":"40 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":204,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":0,"countries":["South Korea"]}],"started":"2021-04-01","startedType":"actual","enrolled":204,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct04536675/","neighbours":{"cancer":[{"id":"resectable-nsclc","kind":"cancer","name":"Resectable stage I to III non-small-cell lung cancer","route":"/cancers/resectable-nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}