{"entity":{"id":"nct03808337","kind":"trial","name":"Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Origina","aka":["PROMISE-005"],"tldr":"A phase 2 trial in triple-negative breast cancer, run by Memorial Sloan Kettering Cancer Center, now recruiting.","summary":"Investigating the Effectiveness of Stereotactic Body Radiotherapy (SBRT) in Addition to Standard of Care Treatment for Cancer That Has Spread Beyond the Original Site of Disease is a phase 2, randomised interventional study registered as NCT03808337 by Memorial Sloan Kettering Cancer Center, with a registry enrolment figure of 145 participants, started 2019-01-16 and due to reach its primary completion in 2027-01. Interventions recorded: Stereotactic Body Radiotherapy/SBRT; Systemic Therapy/Standard of Care. Conditions listed: Triple Negative Breast Cancer; Non Small Cell Lung Cancer; Metastatic Breast Cancer; Metastatic Non-Small Cell Lung Carcinoma. Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT03808337","url":"https://clinicaltrials.gov/study/NCT03808337"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-metastatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03808337","phase":"2","setting":"PROMISE-005: A Phase II Randomized Study Assessing the Efficacy of Stereotactic Body Radiotherapy (SBRT) in Patients With Oligometastatic Breast or Lung Cancer","sponsor":"Memorial Sloan Kettering Cancer Center","participation":[{"nct":"NCT03808337","source":"https://clinicaltrials.gov/study/NCT03808337","fetchedAt":"2026-10-07T16:53:09.552Z","studySha256":"8c26632c81c8832c00e97d35f992c25e5daf244308928334e34f8f5f215d470f","overallStatus":"RECRUITING","lastUpdatePosted":"2026-02-27","leadSponsor":"Memorial Sloan Kettering Cancer Center","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":145,"enrolmentType":"ESTIMATED","siteCount":12,"recruitingSiteCount":11,"countries":["United States"]}],"started":"2019-01-16","startedType":"actual","enrolled":145,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03808337/","neighbours":{"cancer":[{"id":"tnbc-metastatic","kind":"cancer","name":"Metastatic triple-negative breast cancer","route":"/cancers/tnbc-metastatic/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}