{"entity":{"id":"nct03439709","kind":"trial","name":"Multicenter Evaluation of the Effect of Upfront Radiosurgery on Residual Growth Hormone-secreting Pituitary Adenoma","aka":["MERGE"],"tldr":"A phase 3 trial of Gamma Knife in Pituitary tumours, run by Samsung Medical Center, with a status the registry has not verified recently.","summary":"Multicenter Evaluation of the Effect of Upfront Radiosurgery on Residual Growth Hormone-secreting Pituitary Adenoma is a phase 3 interventional study registered as NCT03439709 by Samsung Medical Center, with 90 participants planned, started 2018-03-01 and due to reach its primary completion in 2022-06-30. Interventions recorded: Gamma knife radiosurgery, Lanreotide 60Mg Solution for Injection. Conditions recorded: Acromegaly Due to Pituitary Adenoma.\n\nLinked to the technology Gamma Knife because the registry names it (\"gamma knife\") among its interventions and Pituitary tumours among its conditions. Registry record only: no result has been read by an editor.","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT03439709","url":"https://clinicaltrials.gov/study/NCT03439709"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["pituitary-tumours"],"sections":[],"technologies":["gamma-knife"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03439709","phase":"3","setting":"Multicenter Evaluation of the Effect of Upfront Radiosurgery on Residual Growth Hormone-secreting Pituitary Adenoma From an Endocrinological Point of View (MERGE Study): a Randomized, Phase 3 Trial","sponsor":"Samsung Medical Center","participation":[{"nct":"NCT03439709","source":"https://clinicaltrials.gov/study/NCT03439709","fetchedAt":"2026-10-07T16:53:02.192Z","studySha256":"964152a560cd9184c77db4dd1dccbc5d90fafbfb8b9be5d7f547f30dcfaa7340","overallStatus":"UNKNOWN","lastUpdatePosted":"2018-03-01","leadSponsor":"Samsung Medical Center","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"70 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":90,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":0,"countries":["South Korea"]}],"started":"2018-03-01","startedType":"estimated","enrolled":90,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03439709/","neighbours":{"cancer":[{"id":"pituitary-tumours","kind":"cancer","name":"Pituitary tumours (pituitary neuroendocrine tumours) and pituitary carcinoma","route":"/cancers/pituitary-tumours/"}],"technology":[{"id":"gamma-knife","kind":"technology","name":"Gamma Knife","route":"/technologies/gamma-knife/"}]}}