{"entity":{"id":"nct02685605","kind":"trial","name":"Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme","aka":["INTRAGO II"],"tldr":"A phase 3 trial of Intraoperative radiotherapy in Glioma & glioblastoma, run by Universitätsmedizin Mannheim, active and no longer recruiting.","summary":"Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme is a phase 3 interventional study registered as NCT02685605 by Universitätsmedizin Mannheim, with 314 participants planned, started 2016-12-09 and due to reach its primary completion in 2025-11. Interventions recorded: Standard surgery, Intraoperative radiotherapy, Radiochemotherapy, Temozolomide. Conditions recorded: Glioblastoma.\n\nLinked to the technology Intraoperative radiotherapy because the registry names it (\"intraoperative radiotherapy\") among its interventions and Glioma & glioblastoma among its conditions. Registry record only: no result has been read by an editor.","status":"active","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT02685605","url":"https://clinicaltrials.gov/study/NCT02685605"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["glioblastoma"],"sections":[],"technologies":["intraoperative-radiotherapy"],"targets":[],"drugs":["temozolomide"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT02685605","phase":"3","setting":"A Multicenter Randomized Phase III Trial on INTraoperative RAdiotherapy in Newly Diagnosed GliOblastoma Multiforme (INTRAGO II)","sponsor":"Universitätsmedizin Mannheim","participation":[{"nct":"NCT02685605","source":"https://clinicaltrials.gov/study/NCT02685605","fetchedAt":"2026-10-07T16:52:49.954Z","studySha256":"79d5a3ae702070d8d4a0700cec91b96bd55ed2c16a2ecf670a2363b92e83dcf7","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2025-10-14","leadSponsor":"Universitätsmedizin Mannheim","collaboratorCount":2,"minimumAge":"18 Years","maximumAge":"80 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":314,"enrolmentType":"ACTUAL","siteCount":19,"recruitingSiteCount":0,"countries":["Brazil","Canada","China","Germany","South Korea","Spain","United Kingdom","United States"]}],"started":"2016-12-09","startedType":"actual","enrolled":314,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct02685605/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"technology":[{"id":"intraoperative-radiotherapy","kind":"technology","name":"Intraoperative radiotherapy (IORT)","route":"/technologies/intraoperative-radiotherapy/"}],"drug":[{"id":"temozolomide","kind":"drug","name":"Temozolomide","route":"/drugs/temozolomide/"}]}}