{"entity":{"id":"nct00821860","kind":"trial","name":"Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma","aka":["MesoVATS"],"tldr":"A phase 3 trial of Talc in Mesothelioma and Metastatic cancer, run by Papworth Hospital NHS Foundation Trust, completed.","summary":"Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma is a phase 3 interventional study registered as NCT00821860 by Papworth Hospital NHS Foundation Trust, with 196 participants recorded, started 2003-09 and reaching its primary completion in 2013-02. Interventions recorded: talc, therapeutic thoracoscopy, therapeutic videothoracoscopy. Conditions recorded: Malignant Mesothelioma, Metastatic Cancer.\n\nLinked to the drug Talc because the registry names it among its interventions and Mesothelioma and Metastatic cancer among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00821860","url":"https://clinicaltrials.gov/study/NCT00821860"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["mesothelioma","metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["talc-sclerosant"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00821860","phase":"3","setting":"Prospective Randomised Controlled Trial of Video-Assisted Thoracoscopic (VAT) Cytoreductive Pleurectomy Compared to Talc Pleurodesis in Patients With Suspected or Proven Malignant Mesothelioma","sponsor":"Papworth Hospital NHS Foundation Trust","participation":[{"nct":"NCT00821860","source":"https://clinicaltrials.gov/study/NCT00821860","fetchedAt":"2026-10-07T16:52:14.098Z","studySha256":"7f38fc04f1ded27d32b3da400240bfbaadb0e70e02ec1e164ca0ae50e2ab74f3","overallStatus":"COMPLETED","lastUpdatePosted":"2013-06-28","leadSponsor":"Papworth Hospital NHS Foundation Trust","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":196,"enrolmentType":"ACTUAL","siteCount":5,"recruitingSiteCount":0,"countries":["United Kingdom"]}],"started":"2003-09","enrolled":196,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00821860/","neighbours":{"cancer":[{"id":"mesothelioma","kind":"cancer","name":"Mesothelioma","route":"/cancers/mesothelioma/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"talc-sclerosant","kind":"drug","name":"Talc (intrapleural)","route":"/drugs/talc-sclerosant/"}]}}