{"entity":{"id":"nct00168181","kind":"trial","name":"Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients","aka":[],"tldr":"A phase 3 trial of Pilocarpine in Head and neck squamous cell carcinoma, run by Alberta Health services, completed.","summary":"Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients is a phase 3 interventional study registered as NCT00168181 by Alberta Health services, with 220 participants recorded, started 2002-04. Interventions recorded: Submandibular gland Transfer, Salagen. Conditions recorded: Cancer, Head and Neck Cancer.\n\nLinked to the drug Pilocarpine because the registry names it among its interventions and Head and neck squamous cell carcinoma among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00168181","url":"https://clinicaltrials.gov/study/NCT00168181"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck"],"sections":[],"technologies":[],"targets":[],"drugs":["pilocarpine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00168181","phase":"3","setting":"A Phase III Randomized Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients","sponsor":"Alberta Health services","participation":[{"nct":"NCT00168181","source":"https://clinicaltrials.gov/study/NCT00168181","fetchedAt":"2026-10-07T16:51:57.214Z","studySha256":"9f4d4291dd798a827777bc43beb96eb1bd53fece2a67bb2921d04d08d9595698","overallStatus":"COMPLETED","lastUpdatePosted":"2011-04-18","leadSponsor":"Alberta Health services","collaboratorCount":5,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":220,"enrolmentType":"ESTIMATED","siteCount":1,"recruitingSiteCount":0,"countries":["Canada"]}],"started":"2002-04","enrolled":220,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00168181/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"}],"drug":[{"id":"pilocarpine","kind":"drug","name":"Pilocarpine","route":"/drugs/pilocarpine/"}]}}