{"entity":{"id":"nct00045968","kind":"trial","name":"Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer","aka":[],"tldr":"A phase 3 trial of DCVax-L in Glioma & glioblastoma and Brain and spinal cord tumours, run by Northwest Biotherapeutics, with a status the registry has not verified recently.","summary":"Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer is a phase 3 interventional study registered as NCT00045968 by Northwest Biotherapeutics, with 348 participants planned, started 2006-12 and due to reach its primary completion in 2022-11. Interventions recorded: Dendritic cell immunotherapy. Conditions recorded: Glioblastoma Multiforme, Glioblastoma, GBM, Grade IV Astrocytoma, Glioma, Brain Cancer, Brain Tumor.\n\nLinked to the drug DCVax-L because the registry names it among its interventions and Glioma & glioblastoma and Brain and spinal cord tumours among its conditions. Registry record only: no result has been read by an editor.","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00045968","url":"https://clinicaltrials.gov/study/NCT00045968"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["glioblastoma","brain-tumours"],"sections":[],"technologies":[],"targets":[],"drugs":["dcvax-l"],"companies":["northwest-biotherapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00045968","phase":"3","setting":"A Phase III Clinical Trial Evaluating DCVax®-L, Autologous Dendritic Cells Pulsed With Tumor Lysate Antigen For The Treatment Of Glioblastoma Multiforme (GBM)","sponsor":"Northwest Biotherapeutics","participation":[{"nct":"NCT00045968","source":"https://clinicaltrials.gov/study/NCT00045968","fetchedAt":"2026-10-07T16:51:52.401Z","studySha256":"135bd0dada857726f226b17640676ca3d130b6eed756eb28fc00c53acf0323fc","overallStatus":"UNKNOWN","lastUpdatePosted":"2022-05-18","leadSponsor":"Northwest Biotherapeutics","collaboratorCount":0,"minimumAge":"18 Years","maximumAge":"70 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":348,"enrolmentType":"ESTIMATED","siteCount":86,"recruitingSiteCount":0,"countries":["Canada","Germany","United Kingdom","United States"]}],"started":"2006-12","enrolled":348,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00045968/","neighbours":{"cancer":[{"id":"brain-tumours","kind":"cancer","name":"Brain and spinal cord tumours (all types)","route":"/cancers/brain-tumours/"},{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"drug":[{"id":"dcvax-l","kind":"drug","name":"DCVax-L","route":"/drugs/dcvax-l/"}],"company":[{"id":"northwest-biotherapeutics","kind":"company","name":"Northwest Biotherapeutics","route":"/companies/northwest-biotherapeutics/"}]}}