{"entity":{"id":"mountaintap-30","kind":"trial","name":"A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)","aka":["MountainTAP-30"],"tldr":"A phase 2/3 trial testing Navlimetostat in pancreatic ductal adenocarcinoma, active and no longer recruiting.","summary":"A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30) is a phase 2/3 interventional study registered as NCT07076121, led by Bristol-Myers Squibb, and active but no longer recruiting on the registry. Official title: A Randomised, Phase 2/3 Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion. Planned enrolment is 470 participants (estimated). The study started in 2025-10-23 and primary completion is expected in 2029-05-03. No results have been posted on ClinicalTrials.gov.","status":"active","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT07076121","url":"https://clinicaltrials.gov/study/NCT07076121"}],"tags":["ctgov-ingest"],"related":[],"cancers":["pancreatic","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":["navlimetostat"],"companies":["bms"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07076121","phase":"2/3","setting":"A Randomized, Phase 2/3 Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion","sponsor":"Bristol-Myers Squibb","participation":[{"nct":"NCT07076121","source":"https://clinicaltrials.gov/study/NCT07076121","fetchedAt":"2026-10-07T16:55:23.338Z","studySha256":"45996949961fe418af0db735c8ad6c743de19ee7d6c49d0b5ea7a6195b09f59f","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-06-03","leadSponsor":"Bristol-Myers Squibb","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":470,"enrolmentType":"ESTIMATED","siteCount":269,"recruitingSiteCount":0,"countries":["Argentina","Australia","Austria","Belgium","Brazil","Canada","Chile","China","Colombia","Czechia","Denmark","France","Germany","Greece","Hong Kong","India","Ireland","Israel","Italy","Japan","Malaysia","Mexico","Netherlands","Poland","Romania","Singapore","Slovakia","South Africa","South Korea","Spain","Sweden","Switzerland","Taiwan","Turkey (Türkiye)","United Kingdom","United States"]}],"started":"2025-10-23","startedType":"actual","enrolled":470,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/mountaintap-30/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"drug":[{"id":"navlimetostat","kind":"drug","name":"Navlimetostat","route":"/drugs/navlimetostat/"}],"company":[{"id":"bms","kind":"company","name":"Bristol Myers Squibb","route":"/companies/bms/"}]}}