# Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

Source: https://onco.cc/trials/nct04434040/  
OnCo record `nct04434040` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of atezolizumab and sacituzumab govitecan in triple-negative breast cancer, run by Dana-Farber Cancer Institute, now recruiting.

## Summary

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA). ClinicalTrials.gov record last updated 2026-05-04: recruiting. Enrollment is planned at 40 participants. Primary completion is estimated at 2026-12-30. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications. Registered interventions: Atezolizumab, Sacituzumab govitecan. Registered primary measures: Rate of undetectable circulating tumor cfDNA- 6 Cycles.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-10-06
- Also known as: ASPRIA
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT04434040
- Phase: 2
- Setting: Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
- Sponsor: Dana-Farber Cancer Institute
- Enrolled: 40

## Notes

- ClinicalTrials.gov record last updated 2026-05-04: recruiting. Enrollment is planned at 40 participants. Primary completion is estimated at 2026-12-30. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications.

## Sources

- ClinicalTrials.gov NCT04434040: https://clinicaltrials.gov/study/NCT04434040

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/)
- technologies: [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/), [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- targets: [TROP2](https://onco.cc/targets/trop2/)
- drugs: [Atezolizumab](https://onco.cc/drugs/atezolizumab/), [Sacituzumab govitecan](https://onco.cc/drugs/sacituzumab-govitecan/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)
- institutions: [UCSF Helen Diller Family Comprehensive Cancer Center](https://onco.cc/institutions/ucsf/)

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JSON: https://onco.cc/api/v1/entities/nct04434040.json